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Microfluidic Cell Culture Systems by unknown author

By unknown author

The fields of microfluidics and BioMEMS are considerably impacting cellphone biology examine and functions throughout the program of engineering recommendations to human ailment and illnesses. the size of microfluidic channels are like minded to the actual scale of organic cells, and the numerous benefits of microfluidics make it an enticing platform for brand spanking new innovations in biology.

This new expert reference applies the concepts of microsystems to cellphone tradition functions. The authors offer a completely sensible advisor to the foundations of microfluidic gadget layout and operation and their program to phone tradition strategies. The ensuing booklet is full of options and methods that may be instantly deployed within the lab. both, the insights into phone tradition functions will offer these curious about conventional microfluidics and BioMEMS with an realizing of the categorical calls for and possibilities awarded through organic applications.

The aim is to lead new and researchers and expertise builders to the $64000 parts and state-of-the-practice suggestions that might improve the potency and price in their applied sciences, units and biomedical items.

  • Provides insights into the layout and improvement of microfluidic structures with a particular concentrate on mobile tradition applications
  • Focuses on techniques and strategies for the layout and fabrication of microfluidic structures and units for mobilephone culture
  • Provides balanced assurance of microsystems engineering and bioengineering

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Seliktar, Vascular tissue engineering, Annu. Rev. Biomed. Eng. 3 (2001) 225À243. G. Rheinwald, H. Green, Formation of a keratinizing epithelium in culture by a cloned cell line derived from a teratoma, Cell 6 (1975) 317À330. D. Murray, The physiological principle of minimum work. I. The vascular system and the cost of blood volume, Proc. Natl. Acad. Sci. A. 12 (1926) 207À214. [20] M. LaBarbera, Principles of design of fluid transport systems in zoology, Science 249 (1990) 992À1000. R. Emerson, K.

Sheetz, Local force and geometry sensing regulate cell functions, Nat. Rev. Mol. Cell Biol. 7 (4) (2006) 265À275. CHAPTER Microvascular Networks for Tissue Engineering 2 Jen-Huang Huang, Arul Jayaraman and Victor M. 1 Introduction Interest in developing new capabilities to engineer artificial tissue and organ structures suitable for implantation has intensified during the past decade owing to their enormous untapped life saving potential. , acute physical trauma and severe burns) [1]. A well-known example is cardiovascular disease, a condition impacting over 80 million adults in the United States, contributing to 1 out of every 3 deaths in 2007—many of which occurred in patients awaiting a transplant [2].

S. R. Quake, Versatile, fully automated, microfluidic cell culture system, Anal. Chem. 79 (22) (2007) 8557À8563. -J. -Y. Suh, A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells, Lab Chip 10 (1) (2010) 36À42. -I. Kamei, S. F. Yu, H. Takahashi, E. Gschweng, C. , An integrated microfluidic culture device for quantitative analysis of human embryonic stem cells, Lab Chip 9 (4) (2009) 555À563. [29] N. Korin, A. Bransky, U. Dinnar, S. Levenberg, A parametric study of human fibroblasts culture in a microchannel bioreactor, Lab Chip 7 (5) (2007) 611À617.

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