By Eric D Whitman, Douglas S , M D Reintgen
The cancer heart, St. Louis, MO. Pocket-sized guide for college students and clinicians. themes incorporated: logistics and organizational facets, intraoperative gamma radiation detection and radioguided surgical procedure, cancer lymphatic mapping, sentinel lymph node biopsy, and lymphoscintigraphy. Trim measurement: eight x five inches. Wire-spiral binding. DNLM: surgeries, Operative.
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Extra info for Radioguided Surgery. Vandemecum
Labeling would not be necessary if anticipated doses to the pathology staff are small (< 100 mrem/year; almost certainly true) and if DIS is already implemented since specimens are not discarded for a minimum of 5 days after surgery. 1, the dose to a pathologist from handling radioactive tissue samples is very low and should not prevent initial processing of samples and preliminary histological determinations. Nor is it necessary to take special precautions for more complete processing. However, in the interest of taking simple measures that can make small doses even smaller (ALARA principle), personnel at some institutions delay final processing of the sample for 24 hours.
Patterns of recurrence following a negative sentinel lymph node biopsy in 243 patients with stage I or II melanoma. J Clin Oncol 1998; 16:2253-2260. Turner RR, Ollila DW, Krasne DL, Giuliano AE. Histopathologic validation of the sentinel lymph node hypothesis for breast carcinoma. Ann Surg 1997; 226:271-278. Whitman ED, Frisse ME, Kahn MG. The impact of data sharing on data quality. (Abstract) Joseph E, Brobeil A, Glass F et al. Results of complete lymph node dissection in 83 melanoma patients with positive sentinel nodes.
When the location of the external source corresponds to the sentinel node, the skin site is marked. Because these images consist of counts acquired over only a brief period of time, the quality of the images are poor and it may not be possible to locate some nodes which contain little activity. Additional localizing information, may be obtained by marking anatomic landmarks with a radioactive marker or by using a large uniform source of activity (flood source). Most nuclear medicine facilities have a solid flood source that is used daily to check that the nuclear medicine camera is functioning properly.