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Science of the Placebo: Toward an Interdisciplinanary by Harry Guess, Linda Engel, Arthur Kleinman, John Kusek

By Harry Guess, Linda Engel, Arthur Kleinman, John Kusek

According to a gathering in November 2000, this e-book brings jointly researchers from quite a lot of disciplines to envision the organic, behavioral, social, cultural and moral points on the topic of the placebo impact. views at the necessity for together with a placebo in randomized scientific trials may also be examined.This is the 1st try and study the evidence-base of the placebo impact and should supply vital details for clinicans.

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Extra info for Science of the Placebo: Toward an Interdisciplinanary Research Agenda (Evidence-Based Medicine Workbks.)

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Clearly the use of placebos in practice, inert or otherwise, has not disappeared, nor have occasions for deception. ” Such situations serve as a reminder that the standard of truth-telling cannot be absolute. There are grey areas and there are increasingly complex ethical issues arising out of today’s sophisticated medical technology. Bok observed that we know very little about how practitioners behave today. How common is the provision of placebos? She proposed that when placebos are given they be fully documented in the patient’s file, suggesting that such record-keeping would discourage placebo use.

Amanzio M, Benedetti F. Neuropharmacological dissection of placebo analgesia: expectation-activated opioid systems versus conditioning-activated specific subsystems. J Neurosci 1999;19:484–94. Price DD, Milling LS, Kirsch I, Duff A, Montgomery GH, Nicholls SS. An analysis of factors that contribute to the magnitude of placebo analgesia in an experimental paradigm. Pain 1999;83:147–56. 31 THE SCIENCE OF THE PLACEBO 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 32 Kleinman A. Patients and Healers in the Context of Culture.

5 The consequences of this moment, certainly in terms of our subsequent ability to bring the placebo effect into focus for ourselves, were momentous. It led to the conclusion that bodily symptoms that were “created” by the suggestive power of the mind were something akin to a physiological lie. It led to the suspicion that patients whose symptoms responded to interventions of this sort were not suffering from anything that could be considered a real disease. An irony in all this is that Bernheim’s work on suggestion was not intended by him simply as a debunking project.

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